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Silence Therapeutics raises the volume

TIP UPDATE: Silence Therapeutics is gaining momentum and has announced more deals with big pharma players
April 2, 2008

Silence Therapeutics’ chief executive Jeff Vick knows that sexy science isn't attracting investors - the company's shares have fallen over 60 per cent in the last six months. But it is attracting the interest of big pharma players.

IC TIP: Hold at 39p

The company, formerly known as SR Pharma, demonstrated its deal-making potential in 2007 by signing two major deals with AstraZeneca. The first was finalised in July and involves using Silence Therapeutics' discovery and development technology, primarily in the respiratory field. The group's 'siRNA' technology 'silences' genes which cause disease - a technique that's much sought after by big pharma companies when researching therapeutics.

Of more tangible interest is Silence's receipt of an initial access fee of £7.5m, comprising a payment of £2.5m and an equity investment of £5m. The company’s other major collaborations are with Quark Pharmaceuticals and Pfizer and involve developing a treatment for a macular (eye) degeneration. That project is moving into Phase II studies.

Brokers, however, don't expect the group to make profits until 2010.

SILENCE THERAPEUTICS (SLN)
ORD PRICE:39pMARKET VALUE:£46.8m
TOUCH:39-40p12-MONTH HIGH:150pLOW: 29p
DIVIDEND YIELD:nilPE RATIO:na
NET ASSET VALUE:15p*NET CASH:£10.2m

Year to 31 DecTurnover (£m)Pre-tax profit (£m)Earnings per share (p)Dividend per share (p)
20040.15-3.31-9.71nil
20050.51-3.63-5.89nil
20061.95-3.94-4.02nil
20074.05-5.24-4.39nil
% change+108 - --

*Includes intangible assets of £7.3m, or 6p a share

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